General information
Catalog number
A609737
Size
1 mg
Price
304.00 €
Detailed information
Chemical available in other sizes
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Cas number
This product doesn't have CAS Number
Chemical's molecular weight
530.93
Chemical's main applications
4-(4-Amino-3-fluorophenoxy)-N-(2-fluoro-4-((2-(methyl-d3-carbamoyl)pyridin-4-yl)oxy)phenyl)picolinamide Hydrochloride is the labeled analogue of 4-(4-Amino-3-fluorophenoxy)-N-(2-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)picolinamide Hydrochloride (A609735), an impurity of Regorafenib (R143000), which inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent.
Chemical's category
Amines, Aromatics, Heterocycles, Impurities, Isotope Labelled Compounds
Chemical's formula
C25H17D3ClF2N5O4
Physical properties
No Data Available
Melting temperature
No Data Available
Boiling temperature
No Data Available
Chemical's soluble in
No Data Available
Stability conditions
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Storage
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Description
A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3. In formulas, the group is often abbreviated Me. Such hydrocarbon groups occur in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, it can be found on its own in any of three forms anion, cation or radical. The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed,