3-Keto-N-aminoethyl-N’-aminocaproyldihydrocinnamoyl Cyclopamine

General information

Catalog number

K171000

Size

0,25 mg

Price

413.00 €

Detailed information

Chemical available in other sizes

Please inquire size and price

Stock availability

In Stock

Cas number

306387-90-6

Chemical's molecular weight

697.99

Chemical's main applications

Cyclopamine demonstrates teratogenic properties and has been shown to reverse effects ofoncogenic mutations in Smoothened and Patched.1 The KAAD-Cyclopamine has shown 10-20 fold higher potency than cyclopamine in inhibition of ß-Galactosidase expression in p2Ptch-1- cells, with similar or lower toxicity. KAAD-Cyclopamine compound is unstable in solution.

Chemical's category

Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids,

Other name

KAAD-Cyclopamine; 11-Deoxyjervine

Chemical's formula

C44H63N3O4

Physical properties

Pale Yellow to Light Yellow Solid

Melting temperature

105-111°C

Boiling temperature

No Data Available

Chemical's soluble in

Chloroform (Slightly), Methanol (Slightly)

Stability conditions

No Data Available

Storage

Hygroscopic, -20°C Freezer, Under Inert Atmosphere