4-(3-Fluoro-4-((2-(methyl-d3-carbamoyl)pyridin-4-yl)amino)phenoxy)-N-methylpicolinamide

General information

Catalog number

F593182

Size

2,5 mg

Price

268.00 €

Detailed information

Chemical available in other sizes

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Cas number

This product doesn't have CAS Number

Chemical's molecular weight

398.41

Chemical's main applications

4-(3-Fluoro-4-((2-(methyl-d3-carbamoyl)pyridin-4-yl)amino)phenoxy)-N-methylpicolinamide is the labeled analogue of 4-(3-Fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)amino)phenoxy)-N-methylpicolinamide (F593180), an impurity of Regorafenib (R143000), which inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent.

Chemical's category

Amines, Aromatics, Heterocycles, Impurities, Isotope Labelled Compounds

Chemical's formula

C20H15D3FN5O3

Physical properties

No Data Available

Melting temperature

No Data Available

Boiling temperature

No Data Available

Chemical's soluble in

No Data Available

Stability conditions

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Storage

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Description

A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3. In formulas, the group is often abbreviated Me. Such hydrocarbon groups occur in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, it can be found on its own in any of three forms anion, cation or radical. The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed,